Potential Medicinal Value Salvia Divinorum

Salvia Divinorum Mass Distribution Project.

Potential Medicinal Value Salvia Divinorum

Postby SF » Fri Jan 08, 2010 7:40 pm

Potential Medicinal Value Salvia Divinorum

Click Here, Originally posted on http://www.salviadivinorumblog.com/?p=644
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Re: Potential Medicinal Value Salvia Divinorum

Postby Ulmdorgr » Sat Jan 09, 2010 1:06 am

Can you link the source document(s) that hold these views? Thanks.
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Re: Potential Medicinal Value Salvia Divinorum

Postby SF » Sat Jan 09, 2010 10:37 am

Ulmdorgr wrote:Can you link the source document(s) that hold these views? Thanks.


can i link them ? there is a link to the main site.
i might copy the article over if that's what you mean.
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Re: Potential Medicinal Value Salvia Divinorum

Postby Ulmdorgr » Sat Jan 09, 2010 2:50 pm

I'm just looking for the truth, i.e. medical studies. I'm going to use this post as a way to congregate some resources.

Wikipedia has some additional info: http://en.wikipedia.org/wiki/Salvia_div ... _potential

The section I've linked points to two news articles (not studies):
http://www.alertnet.org/thenews/newsdesk/N24424552.htm
Found at the bottom of the page, Thomas Prisinzano, assistant prof at U of Iowa, discusses rat testing and an attempt at synthesizing a non-hallucinogenic molecule.

http://www.chron.com/disp/story.mpl/front/5076760.html
Bryan L. Roth (the guy who found out how Salvinorin A reacts in the brain), director of the National Institute on Mental Health's Psychoactive Drug Screening Program, professor of pharmacology at the University of North Carolina School of Medicine is quoted as saying, "We think that drugs derived from the active ingredient could be useful for a range of diseases: Alzheimer's, depression, schizophrenia, chronic pain and even AIDS or HIV." However, no source is given to back up his opinions (we'll need to find out if he's written any papers on the subject).

Additional investigations

http://www.psychointegrator.com/?p=274
This article reproduces the Wkipedia article section, also propagating the possible medical value myth. We need hard facts: research papers!

http://www.pcworld.com/article/158165/i ... _drug.html
2009 - Dr. Roland Griffiths, professor of behavioral biology in the Department of Psychiatry and Behavioral Sciences at Johns Hopkins University School of Medicine, is quoted as saying "We would anticipate that if salvia were scheduled it would increase research costs and place undue red tape on the drug, and delay research." "[Roland Griffiths] is applying for a research grant from the National Institutes of Health to study the effects of salvia on humans." Also of interest: "DEA officials would say only that they are in the process of evaluating salvia." We might be closer to getting a federal ban this year...

Another scientist interested in Salvia is John Mendelsohn, who works at the California Pacific Medical Center Research Institute. I'm trying to find more info on him.

I still haven't found white papers (I haven't searched any academic databases yet; but I'd like to see if ANYONE in the general public (the Internet) links to a credible source, aside from the researchers themselves, like Daniel Siebert).

Aha! Success
http://www.erowid.org/plants/salvia/sal ... vey1.shtml
Erowid comes through for us! It gives us two references to check concerning the possible medical values myth:
  1. Roth BL, Baner K, et al. "Salvinorin A: a potent naturally occurring non-nitrogenous kappa opioid selective agonist". Proc Natl Acad Sci. 2002; 99(18):11934-9.
  2. Sheffler DJ, Roth BL. "Salvinorin A: the ‘magic mint' hallucinogen finds a molecular target in the kappa opioid receptor". Trends Pharmacol Sci. 2003; 24(3):107-9.
Although, I'm not sure how I'm going to gain access to these two...
Last edited by Ulmdorgr on Sat Jan 09, 2010 3:12 pm, edited 3 times in total.
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Re: Potential Medicinal Value Salvia Divinorum

Postby SF » Sat Jan 09, 2010 3:06 pm

thanks for the info. Ill see what all i can find about the medicinal value. Keep up the good work
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Re: Potential Medicinal Value Salvia Divinorum

Postby childishaztec » Sat Feb 06, 2010 8:27 pm

Well I read this article about the legal status of Salvia Divinorum.
found here http://www.sagewisdom.org/legalstatus.html

and in it he wrote a letter to congress about all the benefits it has/potential; and thought i'd let you guy know about. http://sagewisdom.org/openlettertolawmakers.pdf
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Re: Potential Medicinal Value Salvia Divinorum

Postby Ulmdorgr » Sun Feb 07, 2010 3:36 am

Excellent link! Thank you. We should all be aware of that letter when attempting to fight against poor legislation in our areas.
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Re: Potential Medicinal Value Salvia Divinorum

Postby Sentia » Tue May 11, 2010 10:30 am

Ulmdorgr, and anyone else who is interested:

I have access to a number of journal databases and have downloaded pretty much all the relevant literature I can find. I have PDF copies of the two articles you mention (Roth et. al., 2002; Scheffler & Roth, 2003) as well as a number of others. I don't want to post them online but feel free to get in touch and I can email you a copy.
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Re: Potential Medicinal Value Salvia Divinorum

Postby Ulmdorgr » Tue May 11, 2010 3:15 pm

Thanks for reviving this topic, this was one of the oldest posts on here (so I forgot about it). I just found a site with free access to the PDF for Roth BL, Baner K, et al. "Salvinorin A: a potent naturally occurring non-nitrogenous kappa opioid selective agonist". Proc Natl Acad Sci. 2002; 99(18):11934-9. here: http://www.pnas.org/content/99/18/11934.full.pdf+html

I can't find the second.

Since the original post, I've acquired about 25 research papers on the topic. The latest of interest is the one that discusses salvinorin A's effects on dopamine levels.
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Re: Potential Medicinal Value Salvia Divinorum

Postby jumbi » Fri Jul 09, 2010 10:39 am

Sentia wrote:Ulmdorgr, and anyone else who is interested:

I have access to a number of journal databases and have downloaded pretty much all the relevant literature I can find. I have PDF copies of the two articles you mention (Roth et. al., 2002; Scheffler & Roth, 2003) as well as a number of others. I don't want to post them online but feel free to get in touch and I can email you a copy.


I would very much like to get in contact with you to receive these PDF documents, my email is [email protected]

I feel that as intelligent human beings we have a responsibility to ourselves to not only explore this reality, but any other possible realities that are within our minds. It is a sickening fact that the closed mined people that have control in this world would bar the way for the ascendance of other opened minded individuals purely on the basis of fear of the unknown. This is an atrocity which cannot and should not be tolerated.

I feel that the more information i can get the more informed and aware i can be in combating the negative stigma people are trying to place on this plant.
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Re: Potential Medicinal Value Salvia Divinorum

Postby Ulmdorgr » Sat Jul 10, 2010 2:37 am

I will post available links in a sticky, tomorrow hopefully (just bump this or PM me if I forget).
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Re: Potential Medicinal Value Salvia Divinorum

Postby Ulmdorgr » Mon Jul 12, 2010 4:26 pm

I made this sticky in the general forum: viewtopic.php?f=18&t=287

Let me know if there is a reason I should post links to the individual articles or to scholarly databases.
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Re: Potential Medicinal Value Salvia Divinorum

Postby reboot31 » Wed Apr 27, 2011 8:24 am

wonderful plant... want to have in our backyard... :)
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